Ashley Slocum

Division/Committee: [BIOT] Division of Biochemical Technology

Small virus-retentive filtration (VRF) is a critical unit operation utilized in the viral clearance package to ensure the viral safety of biotherapeutics. This step is relied upon to provide robust retention (> 4 log10 clearance) of parvovirus, e.g…

Oligo(dT) chromatography can be used for the selective capture of mRNA through the A to T base pairing between the PolyA tail of the mRNA and the dT ligand of the resin…