Functional modification of supramolecular frameworks for enhanced photophysical properties | Poster Board #1111

Supramolecular architectures have been increasingly employed for various applications, such as drug delivery and molecular machines. The versatility of these scaffolds lends them to various functionalizations within the same scaffold, enabling multi-position-functionalization with ease and accuracy. In this study, we have explored the functionalization of supramolecular scaffolds, including (pillar[5]arenes, Noria cages, and resorcinarenes), with bipyridyl-type ligands using aldehyde-phosphonate, click-chemistry, and SN2 chemistry. The resulting functionalized supramolecules were then complexed with transition series metal ions. All products were characterized via 1H, 13 C NMR (1D and 2D), and HRMS. Subsequently, the metal-chelated supramolecular structures were investigated for their photophysical profiles by fluorescence and UV-Vis-based spectroscopy, including excitation, emission, excited state lifetime, and quantum yield. In addition, computational modeling was conducted to further understand/explore the molecular structure and predict absorption/emission spectral profiles for modified supramolecular scaffolds.