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3757791
Chloroquine and virus uptake - recapitulating some basic facts of the effect of chloroquine
Date
August 21, 2022
In the context of fighting SARS-CoV-2 infection, chloroquine and derivatives have been suggested as treatments. It has been argued that the therapeutic effect is based on the modulation of viral uptake and fate. Similarities to the endocytotic uptake of nanoparticles are here used to recapitulate the effect of chloroquine on this process.
[HYBRID SESSION] The nano-bio interface describes the interaction of nanoparticles(surfaces) with biology at different levels, from biomolecules to cells. Important examples include the adsorption of proteins to nanoparticle surfaces, or the binding and internalization of nanoparticles by cells…