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442173
Undergraduate Research Posters: Organic Chemistry:
Organophosphorus (OP) compounds such as pesticides and chemical warfare agents primarily target the enzyme acetylcholinesterase (AChE) in the human body. AChE is a hydrolytic enzyme responsible for the degradation of the neurotransmitter acetylcholine…
Organophosphorus (OP) compounds have toxicity and inhibit acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), leading to a cholinergic crisis and possibly death. The OP-inhibited cholinesterases undergo spontaneous _O_-dealkylations, generating the OP-aged forms…