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_Helicobacter pylori_ is a ubiquitous pathogen associated with duodenal ulcers and stomach cancer. The current treatment of the disease is “triple therapy” but negative side effects and increasing antibiotic resistance have resulted in a pressing need for new, more selective therapies…
Glycans that coat the surface of bacteria are compelling antibiotic targets because they contain distinct monosaccharides that are linked to pathogenesis and are absent from human cells. Disrupting glycan biosynthesis presents a path to inhibit a bacterium’s ability to infect the host…
Fluorescent DNA sensors can bind selectively to nucleic acids in a complex biological mixture, and they exhibit enhanced light emission upon binding to their target…