Molecular dynamics (MD) simulations play a vital role in amyloid aggregation study that is crucial to the therapeutic agent development for Alzheimer’s Disease. The accuracy of MD simulation results strongly depends on the force field (FF) employed…
In a complete amyloid aggregation, monomeric peptides/proteins first form soluble oligomers, following by the formation of large pre-fibrillar and mature fibrillar structures. Both amyloid oligomers and fibrils were found to be toxic to human neural cells…
In a complete amyloid aggregation, monomeric peptides/proteins first form soluble oligomers, following by the formation of large pre-fibrillar and mature fibrillar structures. Both amyloid oligomers and fibrils were found to be toxic to human neural cells…
In a complete amyloid aggregation, monomeric peptides/proteins first form soluble oligomers, following by the formation of large pre-fibrillar and mature fibrillar structures. Both amyloid oligomers and fibrils were found to be toxic to human neural cells…
In a complete amyloid aggregation, monomeric peptides/proteins first form soluble oligomers, following by the formation of large pre-fibrillar and mature fibrillar structures. Both amyloid oligomers and fibrils were found to be toxic to human neural cells…
Machine learning is being increasingly utilized in different research fields for its capability to gather vast quantities of data and then generate a series of prediction models for new input…