Session: Undergraduate Research Posters: Medicinal Chemistry:

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus that was declared a pandemic in March 2020 by the World Health Organization (WHO). In addition to the successful development of vaccines, there has been interest in the identification of small molecule inhibitors of various viral targets that could be used as therapeutic agents. We carried out a virtual screening campaign using an open-source, web-based application called Dock Blaster to search for compounds with the potential to inhibit SARS-CoV-2 helicase. The physicochemical parameters and other features of the top hits were evaluated to identify compounds with favorable properties for further investigation.

Todd Ryder

Appearances