Timothy Wencewicz
Appearances
DateApril 16, 2021Antibiotic resistance is a global health problem. New antibiotics acting on new targets are needed to keep pace with resistance. _Mycobacterium tuberculosis_ (_Mtb_), which causes the TB infection, exports glutamine synthetase (GS) outside the cell during host macrophage infection…Presenter
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SESSION: CURRENT TOPICS IN BIOLOGICAL CHEMISTRY:
DateMarch 20, 2022A common strategy utilized by bacteria for scavenging host iron is to synthesize and secrete iron chelating small molecules known as siderophores. Strains of human pathogenic _Acinetobacter baumannii_ produce up to three siderophores: acinetobactin, baumannoferrin, and fimsbactin…Presenter
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- DateMarch 21, 2022Tetracyclines are an important class of antibiotics that are threatened by an emerging new resistance mechanism, enzymatic antibiotic inactivation…
- DateMarch 22, 2022Under iron deficient environment, strains of soil derived _Streptomyces_ species have been reported to biosynthesize a mixture of desferrioxamines, a class of hydroxamate containing siderophores…
- Hydrogel drug delivery platforms are the subject of a robust and burgeoning industry. In 2021, hydrogel-based drug delivery commanded a 6.4-billion-dollar market that is projected to grow to 10.4 billion by 2027…
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- : [BIOL] Division of Biological Chemistry
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University of FloridaNC State UniversityYale UniversityAssociate Professor, Messiah CollegeUniv. of Maryland, PharmacyAssistant Professor of Chemistry, Ball State UniversitySt. Mary's College of MarylandAssociate Professor of Chemistry, Rhodes CollegeMuhlenberg CollegeAmgen Inc.Professor, Virginia TechUniversity of Arkansas for Medical SciencesAssistant Professor, University of Central FloridaMississippi State UniversityMichigan StateSouthern Illinois University CarbondaleLafayette CollegeUniversity of PennsylvaniaAssociate Professor, Rochester Institute of TechnologyPurdue UniversitySyracuse UniversityPostraguate Researcher; Organic Research Chemist, Eotvos Lorand University ; Femtonics Ltd.University of MichiganLewis UniversityBall State UniversityGraduate Student, Texas A&M UniversityAssistant Professor of Chemistry, Missouri State UniversityScientist, Axion Analytical Labs, IncProfessor, Tufts UniversityAssistant Professor of Chemistry & Biochemistry, Gonzaga UniversityAssociate Professor, Saint Louis UniversityUniversity of Wisconsin-Eau ClaireElizabeth S. Thrall, Ph.D.Assistant Professor of Chemistry, Fordham UniversityAssistant Professor of Basic Research (interim), Weill Cornell Medicine College (WCMC) - : [BIOL] Division of Biological Chemistry
Speakers
University of FloridaNC State UniversityYale UniversityAssociate Professor, Messiah CollegeUniv. of Maryland, PharmacyAssistant Professor of Chemistry, Ball State UniversitySt. Mary's College of MarylandAssociate Professor of Chemistry, Rhodes CollegeMuhlenberg CollegeAmgen Inc.Professor, Virginia TechUniversity of Arkansas for Medical SciencesAssistant Professor, University of Central FloridaMississippi State UniversityMichigan StateSouthern Illinois University CarbondaleLafayette CollegeUniversity of PennsylvaniaAssociate Professor, Rochester Institute of TechnologyPurdue UniversitySyracuse UniversityPostraguate Researcher; Organic Research Chemist, Eotvos Lorand University ; Femtonics Ltd.University of MichiganLewis UniversityBall State UniversityGraduate Student, Texas A&M UniversityAssistant Professor of Chemistry, Missouri State UniversityScientist, Axion Analytical Labs, IncProfessor, Tufts UniversityAssistant Professor of Chemistry & Biochemistry, Gonzaga UniversityAssociate Professor, Saint Louis UniversityUniversity of Wisconsin-Eau ClaireElizabeth S. Thrall, Ph.D.Assistant Professor of Chemistry, Fordham UniversityAssistant Professor of Basic Research (interim), Weill Cornell Medicine College (WCMC) - : [BIOL] Division of Biological Chemistry
Speakers
University of FloridaNC State UniversityYale UniversityAssociate Professor, Messiah CollegeUniv. of Maryland, PharmacyAssistant Professor of Chemistry, Ball State UniversitySt. Mary's College of MarylandAssociate Professor of Chemistry, Rhodes CollegeMuhlenberg CollegeAmgen Inc.Professor, Virginia TechUniversity of Arkansas for Medical SciencesAssistant Professor, University of Central FloridaMississippi State UniversityMichigan StateSouthern Illinois University CarbondaleLafayette CollegeUniversity of PennsylvaniaAssociate Professor, Rochester Institute of TechnologyPurdue UniversitySyracuse UniversityPostraguate Researcher; Organic Research Chemist, Eotvos Lorand University ; Femtonics Ltd.University of MichiganLewis UniversityBall State UniversityGraduate Student, Texas A&M UniversityAssistant Professor of Chemistry, Missouri State UniversityScientist, Axion Analytical Labs, IncProfessor, Tufts UniversityAssistant Professor of Chemistry & Biochemistry, Gonzaga UniversityAssociate Professor, Saint Louis UniversityUniversity of Wisconsin-Eau ClaireElizabeth S. Thrall, Ph.D.Assistant Professor of Chemistry, Fordham UniversityAssistant Professor of Basic Research (interim), Weill Cornell Medicine College (WCMC) - : [BIOL] Division of Biological Chemistry
Speakers
University of FloridaNC State UniversityYale UniversityAssociate Professor, Messiah CollegeUniv. of Maryland, PharmacyAssistant Professor of Chemistry, Ball State UniversitySt. Mary's College of MarylandAssociate Professor of Chemistry, Rhodes CollegeMuhlenberg CollegeAmgen Inc.Professor, Virginia TechUniversity of Arkansas for Medical SciencesAssistant Professor, University of Central FloridaMississippi State UniversityMichigan StateSouthern Illinois University CarbondaleLafayette CollegeUniversity of PennsylvaniaAssociate Professor, Rochester Institute of TechnologyPurdue UniversitySyracuse UniversityPostraguate Researcher; Organic Research Chemist, Eotvos Lorand University ; Femtonics Ltd.University of MichiganLewis UniversityBall State UniversityGraduate Student, Texas A&M UniversityAssistant Professor of Chemistry, Missouri State UniversityScientist, Axion Analytical Labs, IncProfessor, Tufts UniversityAssistant Professor of Chemistry & Biochemistry, Gonzaga UniversityAssociate Professor, Saint Louis UniversityUniversity of Wisconsin-Eau ClaireElizabeth S. Thrall, Ph.D.Assistant Professor of Chemistry, Fordham UniversityAssistant Professor of Basic Research (interim), Weill Cornell Medicine College (WCMC) - DateMarch 28, 2023Fimsbactin A, a siderophore produced by _Acinetobacter baumannii_, contains phenolate-oxazoline, catechol, and hydroxamate metal chelation groups that branch from the α-carbon of a central L-serine unit…
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- DateMarch 28, 2023Tetracycline antibiotics have been an important class of antibacterial agents since the 1940s. However, the inevitable emergence of bacterial resistance continuously threats tetracyclines’ clinical application…
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- DateMarch 28, 2023Hydrogel drug delivery platforms are the subject of a robust and burgeoning industry. In 2021, hydrogel-based drug delivery commanded a 6.4-billion-dollar market that is projected to grow to 10.4 billion by 2027…
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Speakers
- DateMarch 29, 2023Tetracyclines are an important class of antibiotics that are threatened by an emerging resistance mechanism, enzymatic antibiotic inactivation…
- DateAugust 13, 2023Since the beginning of the antibiotic golden age in the 1900s, drugs that target folate metabolism have provided lifesaving treatments for bacterial infections. Unfortunately, resistance has haunted these compounds in recent decades, reducing their effectiveness in the clinic…
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Bisubstrate tetracycline destructase inhibitors that block flavin redox cycling | Poster Board #3914
DateAugust 16, 2023Tetracyclines are an important class of antibiotics threatened by an emerging new resistance mechanism – enzymatic inactivation…
