I used the flipped classroom in my large organic chemistry class for many years. When pandemic came, it was easy for me transition to the online format. This past year we had the hybrid format where the in-person component was a 75-min small-class recitation…
We are studying a group of substituted cyclohexenecarboxylic acids whose enantiomers differ only in the placement of the double bond in the cyclohexene ring. Twelve of such molecules were synthesized before and characterized by X-ray single crystal structures…
We are studying the NMR of a series of substituted cyclohexenecarboxylic acids. It was found that even though the overlapping of signals is minimal in the 1D NMR, it is difficult to assign the peaks on the cyclohexene ring…
Wittig reactions are useful in preparing alkenes from aldehydes or ketones. A greener approach to this reaction is mechanically grinding the reagents with a mortar and pestle…
Most of the large science courses at our university are using recitation model with flipped classroom. In Organic Chemistry, lecture videos are posted online before lectures each week for students to watch at their own time…
The United States National Chemistry Olympiad (USNCO) Program is a three-stage competition for high school students culminating with the selection of four representatives to compete at the International Chemistry Olympiad (IChO)…
Despite their long use in the clinic, antimetabolite chemotherapies impart considerable treatment-associated side-effects. In addition, current agents face several pharmacological limitations, such as low drug half-life, high toxicity, and low bioavailability…
Pharmaceutical Chemistry is offered in our chemistry curriculum in the spring of the fourth year. It has served as the capstone course for our chemistry majors. The course has two main topics. One is drug discovery, design, and development…
Ester prodrugs have rapidly become one of the key innovations in pharmaceutical research and production. They also established their utility in cancer therapy by optimizing drug properties to expand treatment modalities and enhance patient outcomes…