Sarah Reisman

Machine-learned ranking models have been developed for the prediction of substrate-specific cross-coupling reaction conditions. Datasets of published reactions were curated for Suzuki, Negishi, and C–N couplings, as well as Pauson–Khand reactions…

The chemical synthesis of natural products provides an exciting platform from which to conduct fundamental research in chemistry and biology. Our group is currently pursuing the synthesis of a number of structurally complex natural products of diverse origin and with varied biological activity…

The chemical synthesis of natural products provides an exciting platform from which to conduct fundamental research in chemistry and biology…

Transition metal catalysis provides powerful new tactics for carbon–carbon bond formation, which often feature as a cornerstone step in the synthesis of natural products…

Academic-industrial collaborations provide a unique opportunity to address challenging chemistry problems with potential real-world impact. In this seminar, I will highlight two recent collaborations focused on catalytic asymmetric reaction development…

The chemical synthesis of natural products provides an exciting platform from which to conduct fundamental research in chemistry and biology…

Natural products serve as an exciting testing ground for both new and old C–H functionalization reactions. Strategic incorporation of C–H functionalization into synthetic planning can minimize unnecessary redox manipulations and functional group interconversions…

Transition metal catalysis provides powerful new tactics for carbon–carbon bond formation, which often feature as a cornerstone step in the synthesis of natural products…

Cassiabudanol is an oxidized diterpene natural product isolated in 2019 that demonstrates immunostimulative activity. Structurally, cassiabudanol is related to the ryanodane and isoryanodane diterpenes and is a proposed rearrangement product of these well-known antifeedants…

As an emerging technology for bond construction, nickel-mediated reductive cross-electrophile coupling (RCEC) leverages different rates of electrophile activation to achieve selective cross-coupling…

As an emerging technology for bond construction, nickel-mediated reductive cross-electrophile coupling (RCEC) leverages different rates of electrophile activation to achieve selective cross-coupling…

Transition metal-catalyzed reactions represent powerful tactics for carbon-carbon bond formation that have revolutionized the synthesis of natural products and medicinal chemistry leads…

Often it's the unexpected results that lead to interesting discoveries in natural product syntheses. This seminar will share vignettes from our natural product synthesis efforts that highlight unexpected discoveries, and how they shaped – and even improved – the completed total synthesis…

Nitrogen–nitrogen bonds are prevalent motifs in biologically active small molecules and natural products…

The chemical synthesis of natural products provides an exciting platform from which to conduct fundamental research in chemistry and biology…

Transition metal catalysis provides powerful new tactics for carbon–carbon bond formation, which often feature as a key step in the synthesis of natural products and drug candidates…

Research in the Reisman lab centers on the synthesis of complex natural products, with a particular focus on the development of new convergent fragment coupling and annulation strategies…

Retrosynthesis is a central task in organic chemistry that involves iteratively breaking down the target molecule into readily available molecules…

The chemical synthesis of natural products provides an exciting platform from which to conduct fundamental research in chemistry and biology…

The chemical synthesis of natural products provides an exciting platform from which to conduct fundamental research in chemistry and biology…