Robert Stanton

Ligand-based drug design (LBDD) utilizes similarity (in 2D-, 3D- or descriptor space) to existing ligands on a project to determine the fitness of new candidate ligands…

DNA-encoded libraries (DELs), comprising billions of encoded compounds, have emerged as effective tool for small molecule hit discovery. Successful DEL selections against a variety of protein families, including first-in-class targets, have been reported…