Division/Committee: [PHYS: Division of Physical Chemistry]

Advancements in biochemical and molecular research have illuminated cellular functions, yet nanoscale tools to manipulate and study cells have been limited. The emergence of nucleic acid nanotechnology probes now enables the exploration of biophysical behaviors in the extracellular space, cell membrane, and intracellular components. Synthetic DNA nanostructures and devices, with their self-assembling properties, biocompatibility, and versatility, have significantly advanced the understanding of cellular forces, behaviors, and transport. Nanoscale tools such as calipers, membrane engineering structures, and phase-separated coacervates made from synthetic DNA/RNA can dynamically interact with biological systems. This symposium will showcase cutting-edge biophysical tools utilizing synthetic nucleic acid nanotechnology to programmatically interface with cellular environments, offering novel insights into cellular processes.

Remi Veneziano

George Mason University College of Engineering and Computing

Appearances