Recent advances in the rapid detection of the SARS-CoV-2 coronavirus have been achieved through the DETECTR technology, which harnesses the novel CRISPR-Cas12a genome-editing system for nucleic acid detection…
CRISPR-Cas9 is the forefront technology for editing the genome. In this system, the Cas9 protein is programmed with guide RNAs to process DNA sequences that match the guide RNA forming an RNA:DNA hybrid structure…
Cascade is a type 1, class 1 CRISPR-Cas system with a variety of roles in prokaryote defense, specifically against DNA-based viruses. Though defense against viruses is a robust role in and of itself, the utility of these systems does not end here…
CRISPR-Cas12a is an emerging gene editing system that recently came to the forefront with innovative applications such as rapid and ultrasensitive nucleic acid detection…
Cas13a is one of the latest additions in the CRISPR-Cas library that exclusively targets RNA, a remarkable property being leveraged for the development of tools for RNA detection, regulation, and imaging…