Dr. Nikki A Thiele

The use of radioactive metal ions for both therapeutic and diagnostic applications has led to significant advances in the field of nuclear medicine…

High-energy alpha particles emitted by the decay of radioactive isotopes demonstrate great promise for the treatment of cancer. Among the few α-emitting isotopes that possess radiological properties suitable for therapeutic use, Ac-225 and Ra-223 have shown remarkable efficacy in clinical studies…

Rare-earth elements, or lanthanides, are uniquely suited for use in a wide range of applications including magnetic devices, catalysts, and medicine…

Efficiently separating the chemically similar rare earth elements (REEs) into elementally pure compositions is one of the greatest scientific challenges of the 21st century…

Division/Committee: [I&EC] Division of Industrial and Engineering Chemistry

A variety of metal ions that span the entirety of the periodic table have potential applications in nuclear medicine…

Radium-223 (Ra-223) is the first and only alpha particle-emitting radioisotope approved for therapeutic use. It is indicated for the treatment of bone metastases in men with prostate cancer…

The selective separation of ions from an aqueous phase using organophosphorus-based solvent extraction reagents has been widely implemented in rare-earth element recovery, environmental remediation, and laboratory-scale sample purifications…

Conventional recovery of rare earth elements requires brute-force mineral dissolution using strong acids and bases, followed by many rounds of solvent extraction to separate the lanthanides based on their size differences…

With recent advances in isotope production, the routine isolation of an array of new and exotic diagnostic and therapeutic radionuclides is becoming feasible…

Several macromolecules show reverse size selectivity, binding to large, light REs (Rare Earth) rather than the typical small, heavy REs. This desirable quality could lead to selectivity-tuned ligands that are selective for particular REs…

With recent advances in isotope production, the routine isolation of an array of new and exotic diagnostic and therapeutic radionuclides is becoming feasible…

Several macromolecules show reverse size selectivity, binding to large, light REs (Rare Earth) rather than the typical small, heavy REs. This desirable quality could lead to selectivity-tuned ligands that are selective for particular REs…

Efficiently separating the chemically similar rare earth elements (REEs) into elementally pure compositions is one of the greatest scientific challenges of the 21st century…

Neuroendocrine tumors (NETs) are a class of neoplasms originating from neuroendocrine cells that can arise anywhere in the body. Each year, ~12,000 people are diagnosed with NETs in the U.S. The 1- and 5-year mortality rates for patients are ~27.2% and 60…

Auger electrons are low-energy electrons emitted from core atomic orbitals following electron capture…

Structure and function of oil/aqueous interfaces play a key role in a range of applications spanning sample purification, rare-earth element recovery to nuclear waste remediation…

In 2013, radium-223 (as radium dichloride, Xofigo®) received FDA approval for the treatment of metastatic prostate cancer in bone…

Rare earth elements (Ln) are in high demand due to their crucial role in various advanced technologies, including energy systems, communications, electronics, and manufacturing…