Division/Committee: [BIOT: Division of Biochemical Technology]

This session will highlight cutting-edge case studies that demonstrate recent innovations and advancements in upstream process development and manufacturing. Topics of interest include, but are not limited to: Troubleshooting and resolving unexpected challenges in upstream process development, technology transfer, and manufacturing Strategies to control charge variant and glycosylation profiles Development, qualification, and application of bioreactor scale-down models Utilization of computational modeling and digital tools in upstream process development, including computational fluid dynamics Implementation of upstream process analytical technology (PAT) for enhanced bioreactor control Cost reduction strategies in upstream processes Novel approaches to bioreactor harvest ensuring cell or product purity Case studies that integrate multiple of these areas are particularly encouraged, showcasing comprehensive solutions and multi-faceted approaches to common and emerging challenges in the field.

Misaal Patel

Merck & Co Inc

Appearances