Two-dimensional nuclear magnetic resonance (NMR) spectra are used extensively to determine the structure of complex molecules in pharmaceutical and organic chemistry…
While the concept of three-dimensional molecular structures is first introduced to students during their Genral Chemistry sequence, nuclear magnetic resonace (NMR) spectroscopy is usually only taught to students later in Organic Chemistry classes…
Two-dimensional nuclear magnetic resonance (2-D NMR) techniques are important methods for the determination of the structures of complex molecules in organic chemistry. Of these, one of the most widely used is H-H correlation spectroscopy, better known as COSY…
The 1H NMR spectra of a series of 4-Ethylbenzene derivatives have been used to create in-class activities designed to introduce students to the concepts of spin systems and coupling constants, signal resolution issues in spectra, and deuterium exchange…
13C NMR spectroscopy is widely used to give detailed information about the arrangement of carbon atoms within organic molecules. In many ways, 13C NMR is a useful starting point to introduce NMR spectroscopy to undergraduates…
The increased capabilities and reduced cost of benchtop NMR spectrometers make them attractive instruments for use in undergraduate teaching laboratories…
Distortionless Enhancement by Polarization Transfer (DEPT) is a widely used NMR pulse technique. Used in conjunction with 13C NMR, DEPT gives valuable information about the number of hydrogen atoms bonded to particular carbon atoms within a molecule…
The synthesis of imines via the acid-catalyzed condensation of either aldehydes or ketones with primary amines is a commonly studied reaction during the second semester of organic chemistry…