Many proteins do not crystallize on their own, restricting our capacity to determine their structure using techniques such as x-ray crystallography. Chaperone proteins show potential to mitigate this problem by binding to and forcing these recalcitrant proteins into crystals…
We determined the structure of the human Thirty-eight-negative kinase-1 Ubiquitin-Associated domain (TNK1 UBA) and the proposed binding modes of UBA to TNK1…