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Kevin Kish
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Structure-activity relationship (SAR) studies on isonicotinamides as highly selective, brain penetrable, and orally active inhibitors of glycogen synthase kinase-3 (GSK-3) for the potential treatment of Alzheimer’s disease
In our continuing efforts to identify selective GSK-3 inhibitors that can be dosed orally for the treatment of Alzheimer’s disease (AD), we sought replacements for a cyclopropane carboxamide group in a previously reported isonicotinamide chemotype…
Presenter
Guanglin Luo
Scientific Director
,
Bristol Myers Squibb
Speakers
Ling Chen
Swanee Jacutin-Porte
Catherine Burton
Hong Xiao
Prasanna Sivaprakasam
Carol Krause
Yang Cao
Nengyin Liu
Jonathan Lippy
Michelle Nophsker
Kimberly Snow
Wendy Clarke
Joseph Raybon
Vinod Aurora
Rick Pieschl
Praveena Baireedy
Trevor Wojcik
Yu-Wen Li
Yuan Tian
Yang hong
Dianne Bryce
Brad Snyder
Stephanie Keenan
Nino Devidze
Regina Lidge
Amy Easton
Kevin Kish
Hal Lewis
John Macor
Gene Dubowchik