The BS2 enzyme is a serine hydrolase isolated from _Bacillus Subtilis_ that can be used to monitor protein to protein interactions that occur within a cell…
Isolated from the hyperthermophilic bacterium _Thermotoga maritima_, TM0077 is an acetyl esterase enzyme that exhibits a high degree of substrate specificity for small acyl groups…
The synthesis of several cyclopropyl fluorescein esters was accomplished via a divergent synthetic strategy and contributed to a library of fluorescein esters…
Several new aromatic fluorescein diesters were synthesized and added to an existing library of fluorogenic compounds used in the enzymatic assay of esterases…
Esterases are essential enzymes involved in numerous cellular functions such as recycling proteins and mediating signaling pathways. Esterases are also utilized as biocatalysts in the industrial manufacturing of pharmaceuticals and detergents…
Various new aromatic fluorescein diesters were synthesized via a nucleophilic substitution reaction between bis(chloromethyl)fluorescein and carboxylic acids containing aromatic five-membered rings with differing heteroatoms including oxazoles, pyrazoles, and thiazoles…
Human carboxylesterases (CESs) are crucial enzymes involved in drug metabolism through the breakdown of ester-containing drugs into active or inactive forms…
_Thermomyces lanuginosus_ (TLL) is a lipase commonly used in industrial settings for the modification of fats and oils. While many applications of TLL have been examined, the substrate specificity is relatively unknown…