Treatment of infections caused by highly resistant Gram-negative bacteria is a growing concern, especially since some strains are entirely resistant to all clinically available antibiotics; however, the development of novel compounds with broad spectrum activity has drastically slowed…
Catecholic rings are structural components of plant woody tissue and the core of some neurotransmitters, such as dopamine. The cleavage of these rings involves an essential protein catalyst, dioxygenase enzymes…
Catecholamines are interesting compounds that function as neurotransmitters and have also recently been found endogenously as unexpected modulators of the cardiac system. Catecholamines are substrates for aromatic cleavage by powerful dioxygenase enzymes…