Dr. Elena S. Koltun

Elena Koltun, Ph.D. VP Medicinal Chemistry.

Elena is an experienced Medicinal Chemist and a leader with an impressive delivery track record across a variety of therapeutic areas, including oncology. With 20 years of experience in the biotech industry, Elena is passionate about small molecule drug discovery and early development. Having worked previously at Exelixis and Numerate, she has taken many programs from concept stage to first in human. Elena is a co-inventor of Cotellic® (Cobimetinib), a MEK inhibitor developed by Exelixis and marketed by Genentech.

Elena joined Revolution Medicines in 2015 and has made significant contributions to the company's pipeline and development of its unique tri-complex platform. She led chemistry efforts for the RAS Companion Inhibitor RMC-4630, led the team that advanced the RAS(ON) Inhibitor RMC-6236 into development, and made pivotal contributions to the discovery of the clinical candidates RMC-6291 and RMC-5845.

Elena received her Ph.D. in organic chemistry from the University of Minnesota and completed postdoctoral training at the University of Illinois at Chicago. Elena has authored multiple scientific publications and is a co-inventor on over 25 issued patents and applications.