Craig McElroy
Appearances
- DateMarch 21, 2022The inhibition of acetylcholinesterase (AChE) by organophosphorus (OP) nerve agents and pesticides is, thankfully, reversible with the treatment of reactivators, such as 2-pralidoxime (2-PAM)…
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PhD Candidate, The Ohio State University - DateMarch 22, 2022Acetylcholinesterase (AChE) is a vital serine hydrolase found throughout the body and it is responsible for the catalytic hydrolysis of the neurotransmitter acetylcholine…
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PhD Candidate, The Ohio State University - DateMarch 22, 2022Organophosphorus compounds (OPs), taking the form of pesticides or as chemical warfare agents, claim the lives of over 200,000 people each year…
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PhD Candidate, The Ohio State University - DateAugust 24, 2022Organophosphates (OPs) have been in recent news with several emerging cases of nerve agent poisoning of significant personalities and national leaders…
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- DateAugust 23, 2022Organophosphorus pesticides are toxic compounds that are used to kill insects and pests that target cultivable crops…
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- Organophosphorus (OP) compounds such as pesticides and chemical warfare agents primarily target the enzyme acetylcholinesterase (AChE) in the human body. AChE is a hydrolytic enzyme responsible for the degradation of the neurotransmitter acetylcholine…
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- Organophosphorus (OP) compounds such as pesticides and chemical warfare agents primarily target the enzyme acetylcholinesterase (AChE) in the human body. AChE is a hydrolytic enzyme responsible for the degradation of the neurotransmitter acetylcholine…
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- : [BIOL] Division of Biological Chemistry
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University of FloridaNC State UniversityUniversity of Illinois ChicagoPhD Student, The Ohio State UniversityWayne State UniversityAssistant Professor, Eastern Illinois UniversityThe Ohio State University - Organophosphorus (OP) compounds such as pesticides and chemical warfare agents primarily target the enzyme acetylcholinesterase (AChE) in the human body. AChE is a hydrolytic enzyme responsible for the degradation of the neurotransmitter acetylcholine…
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- : [BIOL] Division of Biological Chemistry
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University of FloridaNC State UniversityUniversity of Illinois ChicagoPhD Student, The Ohio State UniversityWayne State UniversityAssistant Professor, Eastern Illinois UniversityThe Ohio State University - : [CHED] Division of Chemical Education
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University of Nevada, RenoUniversity of Notre DameAssociate Professor, Mississippi CollegeIndiana State UniversityNortheastern UnivMuhlenberg CollegeAssociate Professor of Chemistry, Rhodes CollegeHigh Point University, High Point University, High Point, NC, US, academicUniversity of TampaPostdoctoral Research and Teaching Fellow, UNC AshevilleAssistant Professor, Lafayette CollegeMelvin Druelinger, Ph.D.Professor of Chemistry, Colorado State Univ PuebloSalt Lake Community CollegeDenison UniversitySoutheast Missouri State UniversityAllison Hurley Predecki, Ph.D.Associate Professor of Chemistry and Biochemistry, Shippensburg University of PennsylvaniaAssociate Professor, Shippensburg UniversityNorthern Kentucky UniversityTrinity UniversityCollege of the Holy CrossProvidence CollegeDavidson CollegeUSC UpstateProfessor, Eastern Oregon UniversityMichael S. Leonard, Ph.D.Professor of Chemistry, Washington & Jefferson CollegeNaresh Gunaganti, Ph.D.Associate Research Scientist, Northeastern UniversityBaljinder Singh, PhDSenior Research Scientist, Northeastern University, BostonResearch Assistant Professor, Northeastern UniversityWhitworth UniversityProfessor, Penn State Berks - Organophosphorus (OP) compounds such as pesticides and chemical warfare agents primarily target the enzyme acetylcholinesterase (AChE) in the human body. AChE is a hydrolytic enzyme responsible for the degradation of the neurotransmitter acetylcholine…
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- : [BIOL] Division of Biological Chemistry
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University of FloridaNC State UniversityUniversity of Illinois ChicagoPhD Student, The Ohio State UniversityWayne State UniversityAssistant Professor, Eastern Illinois UniversityThe Ohio State University - : [CHED] Division of Chemical Education
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University of Nevada, RenoUniversity of Notre DameAssociate Professor, Mississippi CollegeIndiana State UniversityNortheastern UnivMuhlenberg CollegeAssociate Professor of Chemistry, Rhodes CollegeHigh Point University, High Point University, High Point, NC, US, academicUniversity of TampaPostdoctoral Research and Teaching Fellow, UNC AshevilleAssistant Professor, Lafayette CollegeMelvin Druelinger, Ph.D.Professor of Chemistry, Colorado State Univ PuebloSalt Lake Community CollegeDenison UniversitySoutheast Missouri State UniversityAllison Hurley Predecki, Ph.D.Associate Professor of Chemistry and Biochemistry, Shippensburg University of PennsylvaniaAssociate Professor, Shippensburg UniversityNorthern Kentucky UniversityTrinity UniversityCollege of the Holy CrossProvidence CollegeDavidson CollegeUSC UpstateProfessor, Eastern Oregon UniversityMichael S. Leonard, Ph.D.Professor of Chemistry, Washington & Jefferson CollegeNaresh Gunaganti, Ph.D.Associate Research Scientist, Northeastern UniversityBaljinder Singh, PhDSenior Research Scientist, Northeastern University, BostonResearch Assistant Professor, Northeastern UniversityWhitworth UniversityProfessor, Penn State Berks - : [COMP] Division of Computers in Chemistry
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University of South FloridaAssociate Professor, Messiah CollegeIndiana Univ Purdue Univ IndianapolisUniversity of KentuckyAssociate Professor of Chemistry, University of KentuckyBrooklyn CollegeUniversity of PittsburghUniversity of Texas at El Paso University Research InstituteGeorgia Institute of TechnologyGeorgia Institute of TechPhD student, Carnegie Mellon UniversityPhD Student, Carnegie Mellon UniversityCarnegie Mellon UniversityUniversity of AkronAssociate Professor of Chemistry, Missouri State UniversityRutgers The State University of New JerseyResearch Scientist, Lawrence Berkeley National LaboratoryE O Lawrence Berkeley National LaboratoryAssistant Professor, Massachusetts Institute of TechnologyRutgers UniversityGraduate Student, University of Minnesota Twin CitiesUC BerkeleyUC BerkeleyPostdoctoral Associate, University of MinnesotaUniversity of MinnesotaMassachusetts Institute of TechnologyThe University of Texas at DallasWayne State UniversityCatalytic principles from natural enzymes for design of synthetic catalystsUniversity of MissouriUniversity of California San DiegoPostdoctoral Research Scholar, University of California, San DiegoUniversity of California, San DiegoRice UniversityGraduate Student, University of VictoriaUniversity of MarylandProfessor, Uppsala UniversityRheinisch Westfalische Technische Hochschule Aachen Fakultat fur Mathematik Informatik und NaturwissenschaftenHead of Lab Linked Scientific Knowledge, Technische InformationsbibliothekCalifornia Institute of TechnologyUniversity of California RiversideUniversity of CaliforniaGraduate Student, Rutgers UniversityUniv of Ontario Inst of TechSchrodinger IncMathew D. Halls, Ph.D.Senior Vice President, Materials Science, Schrödinger, Inc.Assistant Professor, Missouri State UniversityAssociate Professor, University of KansasPh.D. Student, Massachusetts Institute of TechnologyStony Brook UniversityCarlos Simmerling, PhDProfessor, SUNY Stony BrookProfessor, Indian Institute of Technology KharagpurAssociate Professor, Western University of Health SciencesAssociate Professor of Chemistry, Centenary UniversityPhD Student, Indian Institute of Technology JammuPennsylvania State UnivTexas A&M UniversityNationwide Children's HospitalUniv. of Maryland, PharmacyUniversity of PittsburghUniv of North CarolinaAssistant Professor, Eastern Illinois UniversityUniversity of Texas at DallasBrown UnivUniversity of South FloridaThe University of OklahomaUniversity of Kentucky College of Arts and SciencesChemistry Graduate Student, University of IowaUniversity of IowaThe University of MississippiPurdue UniversityAssistant Professor, University of FindlayAssociate Professor of Chemistry, University of FindlayJohns Hopkins UniversityJohns Hopkins UniversityUniversity of Illinois at Urbana-ChampaignUniversity of MinnesotaThe University of MemphisApplication Scientist, OptibriumLafayette CollegeIndian Institute of Technology DelhiUniversity of Wisconsin-Eau ClaireComputational Scientist, Pacific Nortwest National LaboratoryGraduate Student Researcher, University of California San DiegoUniversity of PittsburghMichigan State UniversityArgonne National LaboratoryMichigan State UniversityPostdoctoral Research Scholar, Michigan State UniversityMichigan State UniversityStaff Scientist, Sandia National LabsArizona State UniversityProfessor, Haverford CollegeNorth Dakota State UniversityAssociate Professor, North Dakota State UniversityPennsylvania State UniversityTexas A&M UnivIndiana UnivOld Dominion UniversityNorth Dakota State UniversityAssistant Professor, University of South Carolina SystemFlorida Gulf Coast UniversityAssociate Professor, Texas A&M University SystemSyracuse UniversityAssistant Professor, Oakland UniversityNorth Carolina State University - Organophosphorus (OP) compounds such as pesticides and chemical warfare agents primarily target the enzyme acetylcholinesterase (AChE) in the human body. AChE is a hydrolytic enzyme responsible for the degradation of the neurotransmitter acetylcholine…
Speakers
- : [BIOL] Division of Biological Chemistry
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University of FloridaNC State UniversityUniversity of Illinois ChicagoPhD Student, The Ohio State UniversityWayne State UniversityAssistant Professor, Eastern Illinois UniversityThe Ohio State University - : [CHED] Division of Chemical Education
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University of Nevada, RenoUniversity of Notre DameAssociate Professor, Mississippi CollegeIndiana State UniversityNortheastern UnivMuhlenberg CollegeAssociate Professor of Chemistry, Rhodes CollegeHigh Point University, High Point University, High Point, NC, US, academicUniversity of TampaPostdoctoral Research and Teaching Fellow, UNC AshevilleAssistant Professor, Lafayette CollegeMelvin Druelinger, Ph.D.Professor of Chemistry, Colorado State Univ PuebloSalt Lake Community CollegeDenison UniversitySoutheast Missouri State UniversityAllison Hurley Predecki, Ph.D.Associate Professor of Chemistry and Biochemistry, Shippensburg University of PennsylvaniaAssociate Professor, Shippensburg UniversityNorthern Kentucky UniversityTrinity UniversityCollege of the Holy CrossProvidence CollegeDavidson CollegeUSC UpstateProfessor, Eastern Oregon UniversityMichael S. Leonard, Ph.D.Professor of Chemistry, Washington & Jefferson CollegeNaresh Gunaganti, Ph.D.Associate Research Scientist, Northeastern UniversityBaljinder Singh, PhDSenior Research Scientist, Northeastern University, BostonResearch Assistant Professor, Northeastern UniversityWhitworth UniversityProfessor, Penn State Berks - : [COMP] Division of Computers in Chemistry
Speakers
University of South FloridaAssociate Professor, Messiah CollegeIndiana Univ Purdue Univ IndianapolisUniversity of KentuckyAssociate Professor of Chemistry, University of KentuckyBrooklyn CollegeUniversity of PittsburghUniversity of Texas at El Paso University Research InstituteGeorgia Institute of TechnologyGeorgia Institute of TechPhD student, Carnegie Mellon UniversityPhD Student, Carnegie Mellon UniversityCarnegie Mellon UniversityUniversity of AkronAssociate Professor of Chemistry, Missouri State UniversityRutgers The State University of New JerseyResearch Scientist, Lawrence Berkeley National LaboratoryE O Lawrence Berkeley National LaboratoryAssistant Professor, Massachusetts Institute of TechnologyRutgers UniversityGraduate Student, University of Minnesota Twin CitiesUC BerkeleyUC BerkeleyPostdoctoral Associate, University of MinnesotaUniversity of MinnesotaMassachusetts Institute of TechnologyThe University of Texas at DallasWayne State UniversityCatalytic principles from natural enzymes for design of synthetic catalystsUniversity of MissouriUniversity of California San DiegoPostdoctoral Research Scholar, University of California, San DiegoUniversity of California, San DiegoRice UniversityGraduate Student, University of VictoriaUniversity of MarylandProfessor, Uppsala UniversityRheinisch Westfalische Technische Hochschule Aachen Fakultat fur Mathematik Informatik und NaturwissenschaftenHead of Lab Linked Scientific Knowledge, Technische InformationsbibliothekCalifornia Institute of TechnologyUniversity of California RiversideUniversity of CaliforniaGraduate Student, Rutgers UniversityUniv of Ontario Inst of TechSchrodinger IncMathew D. Halls, Ph.D.Senior Vice President, Materials Science, Schrödinger, Inc.Assistant Professor, Missouri State UniversityAssociate Professor, University of KansasPh.D. Student, Massachusetts Institute of TechnologyStony Brook UniversityCarlos Simmerling, PhDProfessor, SUNY Stony BrookProfessor, Indian Institute of Technology KharagpurAssociate Professor, Western University of Health SciencesAssociate Professor of Chemistry, Centenary UniversityPhD Student, Indian Institute of Technology JammuPennsylvania State UnivTexas A&M UniversityNationwide Children's HospitalUniv. of Maryland, PharmacyUniversity of PittsburghUniv of North CarolinaAssistant Professor, Eastern Illinois UniversityUniversity of Texas at DallasBrown UnivUniversity of South FloridaThe University of OklahomaUniversity of Kentucky College of Arts and SciencesChemistry Graduate Student, University of IowaUniversity of IowaThe University of MississippiPurdue UniversityAssistant Professor, University of FindlayAssociate Professor of Chemistry, University of FindlayJohns Hopkins UniversityJohns Hopkins UniversityUniversity of Illinois at Urbana-ChampaignUniversity of MinnesotaThe University of MemphisApplication Scientist, OptibriumLafayette CollegeIndian Institute of Technology DelhiUniversity of Wisconsin-Eau ClaireComputational Scientist, Pacific Nortwest National LaboratoryGraduate Student Researcher, University of California San DiegoUniversity of PittsburghMichigan State UniversityArgonne National LaboratoryMichigan State UniversityPostdoctoral Research Scholar, Michigan State UniversityMichigan State UniversityStaff Scientist, Sandia National LabsArizona State UniversityProfessor, Haverford CollegeNorth Dakota State UniversityAssociate Professor, North Dakota State UniversityPennsylvania State UniversityTexas A&M UnivIndiana UnivOld Dominion UniversityNorth Dakota State UniversityAssistant Professor, University of South Carolina SystemFlorida Gulf Coast UniversityAssociate Professor, Texas A&M University SystemSyracuse UniversityAssistant Professor, Oakland UniversityNorth Carolina State University - DateMarch 30, 2023Organophosphorus (OP) compounds such as pesticides and chemical warfare agents primarily target the enzyme acetylcholinesterase (AChE) in the human body. AChE is a hydrolytic enzyme responsible for the degradation of the neurotransmitter acetylcholine…
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- DateMarch 27, 2023Organophosphorus (OP) agents are responsible for the inhibition of the enzyme acetylcholinesterase (AChE) which is found in erythrocytes, brain synapses, and neuromuscular junctions. AChE contains a catalytic triad of serine-histidine-glutamate residues located within the enzyme active site…
- DateMarch 27, 2023Acetylcholinesterase (AChE) is an enzyme in the body found primarily in erythrocytes, brain synapses, and neuromuscular junctions. Located in the active site of the enzyme, the triad of serine, histidine, and glutamate is where selective hydrolysis of the neurotransmitter acetylcholine occurs…
- DateMarch 28, 2023Drug molecules targeting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could save millions of lives from COVID-19 pandemic, and the USFDA has authorized emergency use of Paxlovid, an investigational medicine, for the treatment of mild-to-moderate COVID-19 in adults and children…
- DateAugust 14, 2023Organophosphorus (OP) compounds such as herbicides and pesticides pose a threat because of their toxicity in cholinesterase inhibition. OP compounds inhibit acetylcholinesterase (AChE) by phosphylation of the catalytic serine residue, resulting in cholinergic crisis and potential death…
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The Ohio State University - DateAugust 17, 2023Organophosphorus (OP) compounds have toxicity and inhibit acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), leading to a cholinergic crisis and possibly death. The OP-inhibited cholinesterases undergo spontaneous _O_-dealkylations, generating the OP-aged forms…
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The Ohio State University - DateAugust 19, 2024Acetylcholinesterase (AChE) is an important enzyme for human health. AChE relaxes nerve impulses through hydrolysis of the neurotransmitter acetylcholine. Organophosphorus (OP) compounds are toxic due to their ability to inhibit and age AChE, which induces a cholinergic crisis…
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The Ohio State University - DateAugust 19, 2024Organophosphorus (OP) compounds have been used around the world throughout the twentieth century, often with deadly consequences, while organophosphate pesticides have been used predominantly in developing countries and are often produced on large scales…
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