Session: Physical Chemistry Poster:

Molecular dynamics of intracellular lipid binding proteins, iLBPs, (Fatty Acid Binding Proteins,
FABP5) in different forms, apo and holo form, will be stimulated when bound to arotinoid acid.
The molecular dynamics presented throughout this paper give an insight on how the arotinoid
acid binds with the FABP5. As the FABP5 moves to the different forms, it can be shown how the
arotinoid acid binds and reacts differently. The binding can affect the functionality of the
arotinoid acid. Arotinoid acid is essential as it acts a retinoic acid receptor, RAR. RAR are a type
of nuclear receptors of ligand-activated transcription factors. Activating the transcription of
target genes when they are in ligands’ presences is their main function. Understanding the
binding in molecular dynamics will further understand the functionality of arotinoid acid.

Chrystal Bruce

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