Brian Stoltz
California Inst of Technology
Appearances
DateApril 8, 2021Our laboratory is deeply interested in the discovery and development of new reaction methodology _en route_ to the chemical synthesis of complex bioactive molecules…Presenter
California Inst of Technology
DateJuly 8, 2021Division/Committee: [ORGN] Division of Organic ChemistryOrganizers
Merck Research LabsCalifornia Inst of Technology- DateAugust 23, 2021Division/Committee: [ORGN] Division of Organic Chemistry
Organizers
Merck Research LabsCalifornia Inst of TechnologyPresider
Merck Research Labs - DateAugust 23, 2021Division/Committee: [ORGN] Division of Organic Chemistry
Organizer, Presiders
Merck Research LabsCalifornia Inst of Technology - DateAugust 25, 2021The fundamental step responsible for enantioinduction in the inner-sphere asymmetric Tsuji allylic alkylation is C–C bond formation through a unique seven-membered pericyclic transition state…
Presenter
Speakers
California Inst of Technology - DateAugust 24, 2022Division/Committee: [ORGN] Division of Organic Chemistry
Organizer, Presiders
Merck Research LabsCalifornia Inst of Technology - DateAugust 22, 2022The author will discuss the experience of building a research lab at Caltech with Bob Grubbs as a colleague, neighbor, collaborator, and friend…
Presenter
California Inst of Technology - DateAugust 16, 2023DIVISION/COMMITTEE: [ORGN] Division of Organic Chemistry
Organizer, Presider
Merck Research LabsOrganizer
California Inst of Technology - DateAugust 13, 2023Spirocyclic lactones are valuable structural motifs present in various bioactive natural products. Lactones can be readily converted to other useful functionality, adding to the attractive nature of this structural motif in the discovery of new pharmaceuticals…
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Speakers
California Inst of Technology - DateMarch 17, 2024Nitrogen–nitrogen bonds are prevalent motifs in biologically active small molecules and natural products…
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Speakers
Corteva AgriscienceCalifornia Inst of Technology - DateMarch 18, 2024Our laboratory is deeply interested in the discovery and development of new reaction methodology _en route_ to the chemical synthesis of complex bioactive molecules…
Presenter
California Inst of Technology - DateMarch 17, 2024In 2021, hypermoin A was isolated from the flowers of _Hypercium monogynum_. It is a rearranged nor-polycyclic polyprenylated acylphloroglucinol (norPPAP) containing an unprecedented 7/6/6/5 tetracyclic core and six stereocenters including two all carbon quaternary centers…
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Speakers
- DateAugust 19, 2024DIVISION/COMMITTEE: [ORGN] Division of Organic Chemistry
Organizer, Presiders
Merck Research LabsCalifornia Inst of Technology - DateMarch 23, 2025The total synthesis of complex natural products serves as a driving force for new discoveries in reaction development. This lecture will show how our synthesis of strempeliopidine led to the development of a non-directed Petasis reaction…
Presenter
Co-Authors
- DateMarch 27, 2025We report our efforts toward the total synthesis of Hypermoin A, a rearranged nor-polycyclic polyprenylated acylphloroglucinol (PPAP) natural product with an unusual 7/6/6/5 tetracyclic core…
Presenter
Co-Authors
- DateMarch 25, 2025Our laboratory is deeply interested in the discovery and development of new reaction methods _en route_ to the chemical synthesis of complex bioactive molecules…
Presenter
California Inst of Technology - DateMarch 24, 2025Palladium catalysis has proven an invaluable tool for synthetic chemists as evidenced by its widespread adoption in the fine chemical industries and continued investigation in academic settings…
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Co-Authors
- DateMarch 25, 2025Methods to directly incorporate amide groups are valuable due to the group’s high bioactivity and prevalence in pharmaceuticals and natural products…
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Co-Authors
California Inst of Technology - DateMarch 24, 2025The synthesis of enantioenriched spirocyclic building blocks bearing an all-carbon quaternary center remains an ongoing challenge in the field of organic synthesis…
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