Associate professor of analytical chemistry at Emmanuel College in Boston, MA. Conducting analytical and biomaterials research with undergraduate students for over 12 years: http://gerdonlab.blogs.emmanue....
Social justice involves the equitable participation of all people in ways that are affirming and respectful. Issues of social injustice often focus on the challenges facing poor and marginalized populations worldwide and share a common thread with the UN Sustainable Development Goals (SDGs)…
Collagen is a structural protein that acts as a scaffold for the calcium phosphate mineralization reaction that forms bone. In order to better understand this mineralization reaction, collagen hydrogels have been synthesized and mineralized biomimetically…
A range of nanomaterials have been previously studied as biomimetic temples for mineralization when presenting bioinspired functional groups such as peptides and nucleotides. DNA aptamers have recently been selected to influence calcium mineral formation using a novel precipitation SELEX method…
A survey of over 300 instructors of undergraduate analytical chemistry was conducted in 2021 with the aim of learning what topics are currently prioritized in analytical and instrumental chemistry lectures and labs…
Instructors in chemistry are motivated to deliver content and improve student understanding of the physical and chemical world. Doing this while ignoring student’s personal connections, experiences, and emotions – positive or negative - may undermine the educational goal…
Instructors in chemistry are motivated to deliver content and improve student understanding of the physical and chemical world. Doing this while ignoring student’s personal connections, experiences, and emotions – positive or negative - may undermine the educational goal…
Instructors in chemistry are motivated to deliver content and improve student understanding of the physical and chemical world. Doing this while ignoring student’s personal connections, experiences, and emotions – positive or negative - may undermine the educational goal…
Instructors in chemistry are motivated to deliver content and improve student understanding of the physical and chemical world. Doing this while ignoring student’s personal connections, experiences, and emotions – positive or negative - may undermine the educational goal…
Collagen is a known biological structural scaffold that is important in the calcium phosphate mineralization of bone. Real-time, kinetic analysis of collagen mineralization has not previously been reported with good time resolution…
Instructors in chemistry are motivated to deliver content and improve student understanding of the physical and chemical world. Doing this while ignoring student’s personal connections, experiences, and emotions – positive or negative - may undermine the educational goal…
Bone formation involves the mineralization of calcium phosphate within the fibers of collagen and requires a variety of non-collagenous proteins in controlling the process. Biomimetic molecules, such as selected ssDNA aptamers, could be used to promote the same intrafibrillar mineralization…
Gold nanoparticles with a variety of ligands were found to act as biomimetic templates for the mineralization of calcium phosphate. Gold nanoparticles are useful scaffold for the development of multi-functional materials due to their ease of synthesize and functionalization…
In the process of bone formation, collagen fibrils are a major structural component for the growth of calcium phosphate mineral. In the event bone cannot regenerate, biomimetic scaffolds could potentially replace artificial repair materials and usurp the role of collagen in bone formation…
Calcium phosphate mineralization is an important process relating to bone and enamel formation in vivo. A wide range of biomimetic template molecules have been studied to direct the process of mineralization, including poly-aspartic acid, DNA aptamers, and gold nanoparticles…
Secondary osteogenesis is a process in bone formation where the collagen fibrils are assembled into a highly organized lamellar structure and result in intrafibrillar mineralization…
DNA origami nanostructures that mimic native collagen fibrils have been assembled to enhance hydroxyapatite mineralization and improve bone regeneration…
Hydroxyapatite (Ca5(PO4)3OH) mineralization is integral to native bone formation and is a process controlled by extracellular proteins in vivo. Functionalized gold nanoparticles have been studied as protein mimics and have been shown to influence the mineralization process…
Gold monolayer protected nanoparticles (NP) have been widely studied and applied in sensors, catalysis, and imaging. The possibilities of gold NPs as protein mimics is likewise expanding due to the versatile scaffold afforded on which to present a wide range of functional molecules…
Bones are primary composed of type 1 collagen and hydroxyapatite (Ca5(PO4)3OH, HAP). Intrafibrillar mineralization, a highly organized type of mineralization that results in a strong lamellar structure, is influenced by collagen and non-collagenous proteins (NCP)…