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MEDI Award Session I:
02:00pm - 05:45pm USA / Canada - Central - August 21, 2022 | Location: W182 (McCormick Place Convention Center)
Dr. Maria-Jesus Blanco, Organizer; Amanda Bryant-Friedrich, Organizer, Presider
Division: [MEDI] Division of Medicinal Chemistry
Session Type: Oral - In-person
Division/Committee: [MEDI] Division of Medicinal Chemistry
Sunday
Introductory Remarks
02:00pm - 02:10pm USA / Canada - Central - August 21, 2022 | Location: W182 (McCormick Place Convention Center)
Division: [MEDI] Division of Medicinal Chemistry
Session Type: Oral - In-person

Sunday
3734770 - David W. Robertson award: Expanding opportunities for targeting RNA-binding proteins
02:10pm - 03:00pm USA / Canada - Central - August 21, 2022 | Location: W182 (McCormick Place Convention Center)
Amanda Garner, Presenter
Division: [MEDI] Division of Medicinal Chemistry
Session Type: Oral - In-person
Cellular RNAs are known to be invariably bound to and often modified by RNA-binding proteins (RBPs). Accordingly, RBPs play key roles in regulating many aspects of coding and non-coding RNA biology, including RNA processing, nuclear export, cellular transport, function, localization, and stability. Disruption of the complex network of RNA-protein interactions (RPIs) has been implicated in a number of human diseases including neurodegenerative, neuromuscular, neurodevelopmental and cardiovascular diseases, encephalo-, ribosomo- and neuropathies, autoimmune disorders, and many types of cancer. Thus, the targeting of RBPs and RPIs has arisen as a new frontier in RNA-targeted drug discovery. In this talk, I will discuss our laboratory’s efforts towards the development and application of innovative assay technologies, as well as rational medicinal chemistry approaches, for targeting RPIs to enable the discovery of novel RNA-targeted therapeutics.
Sunday
3742053 - Division of medicinal chemistry award lecture the arc of innovation in small molecule drug discovery: Past, present and future
03:00pm - 03:50pm USA / Canada - Central - August 21, 2022 | Location: W182 (McCormick Place Convention Center)
Dr. Lawrence Hamann, Presenter
Division: [MEDI] Division of Medicinal Chemistry
Session Type: Oral - In-person
This talk will focus on reflections in the evolution of small molecule drug discovery over three decades, and an outlook for the future.
Sunday
Intermission
03:50pm - 04:05pm USA / Canada - Central - August 21, 2022 | Location: W182 (McCormick Place Convention Center)
Division: [MEDI] Division of Medicinal Chemistry
Session Type: Oral - In-person

Sunday
3768432 - Philip S. Portoghese Journal of Medicinal Chemistry/ACS Medicinal Chemistry Letters/Division of Medicinal Chemistry Joint Lectureship Award for an Established Investigator
04:05pm - 04:55pm USA / Canada - Central - August 21, 2022 | Location: W182 (McCormick Place Convention Center)
R. Kip Guy, Presenter
Division: [MEDI] Division of Medicinal Chemistry
Session Type: Oral - In-person
The recipient of the Philip S. Portoghese Journal of Medicinal Chemistry/ACS Medicinal Chemistry Letters/Division of Medicinal Chemistry Joint Lectureship Award for an Established Investigator will present an award lecture.
Sunday
3768457 - Philip S. Portoghese Journal of Medicinal Chemistry/ACS Medicinal Chemistry Letters/Division of Medicinal Chemistry Joint Lectureship Award for Young Investigator
04:55pm - 05:45pm USA / Canada - Central - August 21, 2022 | Location: W182 (McCormick Place Convention Center)
Michael Bollong, Presenter
Division: [MEDI] Division of Medicinal Chemistry
Session Type: Oral - In-person
The recipient of Philip S. Portoghese Journal of Medicinal Chemistry/ACS Medicinal Chemistry Letters/Division of Medicinal Chemistry Joint Lectureship Award for Young Investigator will present the award lecture.